徐海明，男，汉族，副教授，硕士研究生导师。1986年10月生，山东高唐人。博士毕业于中国科学院生态环境研究中心。主要学术荣誉包括：中国科学院"西部青年学者"、宁夏回族自治区"青年托举人才"、宁夏医科大学"自治区级学术技术带头人后备培育对象"。现任中华医学会地方病分会砷中毒学组委员，并担任由南京大学与生态环境部南京环境科学研究所联合创办的英文学术期刊Eco-Environment & Health（EEH）青年编委，同时兼任宁夏老年医学会职业病专业委员会常务委员。主持国家级、省部级、厅局级科研课题10余项，发表科研论文20余篇，授权国家发明专利2项，实用新型专利4项，均已完成科技成果转化。研究成果发表在 Environmental Health Perspectives、Environmental Pollution、Ecotoxicology and Environmental Safety等国际权威期刊上。

联系方式：

联系电话：13469597910

电子邮箱：xuhaiming5689467@163.com

主要科研项目：

1. 国家自然科学基金委员会，煤工尘肺患者体内乙酰胆碱酯酶活性的变化及其调控机制，2017.01-2020.12，33万，主持

2. 宁夏自然科学基金优秀青年项目，自噬关键基因ATG7在实验性矽肺中的作用及汉防己甲素对其保护作用的分子机制研究，2022.03-2025.03，20万，主持

3. 教育部春晖计划，葡萄籽多酚对PFOS所致大鼠胰岛瘤INS-1细胞GSIS损伤的保护作用，2017.01-2019.12，2万，主持

4. 中科院西部之光，黄河流域宁夏段有机磷酸酯的环境暴露特征和生态健康效应研究，2024.01-2025.12，10万，主持

代表性论文：

1. Zhang YF, Shan C, Wang Y, Qian LL, Jia DD, Zhang YF, Hao XD, Xu HM. Cardiovascular toxicity and mechanism of bisphenol A and emerging risk of bisphenol S. Sci Total Environ. 2020 Jun 25;723:137952.

2. He B, Xu HM, Liu HW, Zhang YF. Unique regulatory roles of ncRNAs changed by PM2.5 in human diseases. Ecotoxicol Environ Saf. 2023 Apr 15;255:114812. doi: 10.1016/j.ecoenv. 2023. 114812. Epub 2023 Mar 22. PMID: 36963186.

3. Lin YJ, Li HM, Gao YR, Wu PF, Cheng B, Yu CL, Sheng YX, Xu HM. Environmentally relevant concentrations of benzophenones exposure disrupt intestinal homeostasis, impair the intestinal barrier, and induce inflammation in mice. Environ Pollut. 2024 Apr 11; 350:123948. doi: 10.1016/j.envpol. 2024. 123948. Epub ahead of print. PMID: 38614423.

4. Wang Y, Shan J, Zhang L, Wang R, Wu MY, Li HM, Xu HM. The role of FAM171A2-GRN-NF-κB pathway in TBBPA induced oxidative stress and inflammatory response in mouse-derived hippocampal neuronal HT22 cells. Ecotoxicol Environ Saf. 2024 Nov 30; 289: 117445.

5. He B, Xu HM, Li SW, Zhang YF, Tian JW. Emerging regulatory roles of noncoding RNAs induced by bisphenol a (BPA) and its alternatives in human diseases. Environ Pollut. 2024 Sep 15; 357:124447.

6. Zuo YB, Wen ZJ, Cheng MD, Jia DD, Zhang YF, Yang HY, Xu HM, Xin H, Zhang YF. The pro-atherogenic effects and the underlying mechanisms of chronic bisphenol S (BPS) exposure in apolipoprotein E-deficient mice. Ecotoxicol Environ Saf. 2024 Oct 15; 285: 117133.

7. Li HM, Gao YR, Chang Q, Pei XY, Sun JH, Lin YJ, Tian YN, Qiang-Wang, Zhao B, Xie HQ, Ma HM, Xu HM. BP-3 exposure at environmentally relevant concentrations induced male developmental reproductive toxicity via ER/CCL27/ROS pathway in mice. Ecotoxicol Environ Saf. 2024 Dec 16; 290:117556.

8. Li, H.-M.; Gao, Y.-R.; Liu, C.; Sheng, Y.-X.; Pu, Y.-J.; Sun, J.-H.; Tian, Y.-N.; Yang, L.; Ma, H.-M.; Xu HM. Preliminary Study on the Positive Expression Regulation of Alpha2-Macroglobulin in the Testicular Tissue of Male Mice by Environmental Estrogens. Int. J. Mol. Sci. 2024, 25, 13434.

9. Wang ZY, Wen ZJ, Xu HM, Zhang Y, Zhang YF. Exosomal noncoding RNAs in central nervous system diseases: biological functions and potential clinical applications. Front Mol Neurosci. 2022 Nov 9; 15: 1004221.

10. Li J, Wang Y, Wang R, Wu MY, Shan J, Zhang YC, Xu HM. Study on the molecular mechanisms of tetrandrine against pulmonary fibrosis based on network pharmacology, molecular docking and experimental verification. Heliyon. 2022 Aug 13; 8(8): e10201.