徐海明，博士毕业于中国科学院生态环境研究中心，现为宁夏医科大学公共卫生学院教授，实验教学中心主任，硕士研究生导师，中国科学院西部青年学者、宁夏青年托举人才、宁夏医科大学自治区级学术技术带头人后备培育对象。现为中华医学会地方病分会砷中毒学组委员，中国医学救援协会公共卫生分会理事，宁夏老年医学会职业病专业委员会常务委员，南京大学和生态环境部南京环境科学研究所共同创立的英文期刊 Eco-Environment & Health的青年编委。主持国家级、省部级、厅局级科研课题 10 余项，发表科研论文 20 余篇，授权国家发明专利 2 项，实用新型专利 4 项，均已完成科技成果转化。研究成果发表在 Environmental Health Perspectives、Environmental Pollution、Ecotoxicology and Environmental Safety等国际高水平期刊上。论文被引707次，H-index为14。

研究方向：职业卫生与环境卫生

联系方式：

地址：宁夏银川市兴庆区胜利街1160号

办公室：臻善楼205室

电话：13469597910

邮箱：xuhaiming1986@nxmu.edu.cn

主要科研项目：

1. 国家自然科学基金委员会，煤工尘肺患者体内乙酰胆碱酯酶活性的变化及其调控机制，2017.01-2020.12，33万，主持

2. 宁夏自然科学基金优秀青年项目，自噬关键基因ATG7在实验性矽肺中的作用及汉防己甲素对其保护作用的分子机制研究，2022.03-2025.03，20万，主持

3. 教育部春晖计划，葡萄籽多酚对PFOS所致大鼠胰岛瘤INS-1细胞GSIS损伤的保护作用，2017.01-2019.12，2万，主持

4. 中国科学院西部之光，黄河流域宁夏段有机磷酸酯的环境暴露特征和生态健康效应研究，2024.01-2025.12，10万，主持

代表性论文：

1. Zhang YF, Shan C, Wang Y, Qian LL, Jia DD, Zhang YF, Hao XD, Xu HM. Cardiovascular toxicity and mechanism of bisphenol A and emerging risk of bisphenol S. Sci Total Environ. 2020 Jun 25;723:137952.

2. He B, Xu HM, Liu HW, Zhang YF. Unique regulatory roles of ncRNAs changed by PM2.5 in human diseases. Ecotoxicol Environ Saf. 2023 Apr 15;255:114812. doi: 10.1016/j.ecoenv. 2023. 114812. Epub 2023 Mar 22. PMID: 36963186.

3. Lin YJ, Li HM, Gao YR, Wu PF, Cheng B, Yu CL, Sheng YX, Xu HM. Environmentally relevant concentrations of benzophenones exposure disrupt intestinal homeostasis, impair the intestinal barrier, and induce inflammation in mice. Environ Pollut. 2024 Apr 11; 350:123948. doi: 10.1016/j.envpol. 2024. 123948. Epub ahead of print. PMID: 38614423.

4. Wang Y, Shan J, Zhang L, Wang R, Wu MY, Li HM, Xu HM. The role of FAM171A2-GRN-NF-κB pathway in TBBPA induced oxidative stress and inflammatory response in mouse-derived hippocampal neuronal HT22 cells. Ecotoxicol Environ Saf. 2024 Nov 30; 289: 117445.

5. He B, Xu HM, Li SW, Zhang YF, Tian JW. Emerging regulatory roles of noncoding RNAs induced by bisphenol a (BPA) and its alternatives in human diseases. Environ Pollut. 2024 Sep 15; 357:124447.

6. Zuo YB, Wen ZJ, Cheng MD, Jia DD, Zhang YF, Yang HY, Xu HM, Xin H, Zhang YF. The pro-atherogenic effects and the underlying mechanisms of chronic bisphenol S (BPS) exposure in apolipoprotein E-deficient mice. Ecotoxicol Environ Saf. 2024 Oct 15; 285: 117133.

7. Li HM, Gao YR, Chang Q, Pei XY, Sun JH, Lin YJ, Tian YN, Qiang-Wang, Zhao B, Xie HQ, Ma HM, Xu HM. BP-3 exposure at environmentally relevant concentrations induced male developmental reproductive toxicity via ER/CCL27/ROS pathway in mice. Ecotoxicol Environ Saf. 2024 Dec 16; 290:117556.

8. Li, H.-M.; Gao, Y.-R.; Liu, C.; Sheng, Y.-X.; Pu, Y.-J.; Sun, J.-H.; Tian, Y.-N.; Yang, L.; Ma, H.-M.; Xu HM. Preliminary Study on the Positive Expression Regulation of Alpha2-Macroglobulin in the Testicular Tissue of Male Mice by Environmental Estrogens. Int. J. Mol. Sci. 2024, 25, 13434.

9. Wang ZY, Wen ZJ, Xu HM, Zhang Y, Zhang YF. Exosomal noncoding RNAs in central nervous system diseases: biological functions and potential clinical applications. Front Mol Neurosci. 2022 Nov 9; 15: 1004221.

10. Li J, Wang Y, Wang R, Wu MY, Shan J, Zhang YC, Xu HM. Study on the molecular mechanisms of tetrandrine against pulmonary fibrosis based on network pharmacology, molecular docking and experimental verification. Heliyon. 2022 Aug 13; 8(8): e10201.